BBC News correspondents are on the scene with the latest details.
Alison Freeman : Edgware Road Underground Station : 1245 BST
There are hordes of press here but it's difficult to contact the office because the phone networks are down. The whole area is cordoned off and there are crowds of people at the cordons.
There are several fire engines and ambulances coming in and out all the time, although I haven't seen any injured people. At St Mary's Hospital there are staff standing outside waiting for people to come in - there is a constant stream of fire engines, but it is quite calm.
Ben Davies : Tavistock Square : 1241 BST
I have just cycled across central London which has been hit by major road closures with few vehicles about except ambulances and police vans.
Near the scene of the Tavistock Square bus attack Euston Road is shut as is nearby Russell Square.
My route took me from Bloomsbury via Soho and Trafalgar Square to the BBC Westminster offices. The normally bustling West End is eerily quiet apart from people trying to get to work and the odd determined tourist.
In Tavistock Square the wreckage of the roofless red London bus sits outside the offices of the British Medical Association, newspapers blowing in the road. A symbol of an ordinary Thursday morning commute cruelly interrupted.
Andrew Winstanley : Liverpool Street : 1239 BST
The station is still closed and all the shops are being closed with people still inside; there seems to be a general lockdown.
Police are going from door to door searching apartments above shops to check them out. There is concern that there may be more undetected devices.
Jeff Randall : City of London : 1235 BST
There are lots of men in suits coming out of the City of London - clearly they couldn't leave their offices and get on to the tubes and taxis so they're simply walking home - it's an extraordinary sight.
The emergency services are really rallying the troops. As I battled in from Essex ambulances and police cars were pouring in from Essex to try to shore up the job the emergency services are doing here. As for the City itself, trading is remarkably calm. There's a very low level of trading largely because many of the big banks have evacuated their offices.
Fergal Parkinson : Tavistock Square : 1220 BST
I'm outside the British Medical Association on Tavistock Square where a lot of the injured are still being treated. People are lying on the ground being treated by paramedics and doctors - some of whom obviously work at the BMA.
Five ambulances have arrived and are taking a few more people away as well. There's also a large ambulance with seats on board and people are starting to walk on to that vehicle. I've also seen blood supplies arrive - three vans from the National Blood Service with blue lights flashing.
Guto Hari : BBC Television Centre : 1210 BST
Tony Blair has talked on many occasions about what keeps him awake at night. And it seems that his worst nightmare is now happening. In his statement he was very calm and determined, saying he was going to return to London. He wants to speak to the people who have suffered, and actually try and get to grips with the situation.
There are well established procedures in place. Which is why we're seeing all these emergency procedures being put in place, such as transport being shut down. They have been preparing for this.
John Pienaar : Gleneagles : 1209 BST
The first confirmation that these are being treated as terrorist attacks and the prime minister is sending two messages - firstly of course of sympathy for the victims, and secondly a message of defiance to the terrorists.
The visible evidence is that he will return to London in a couple of hours to be briefed by senior officers and then return to the G8 summit later to carry on. All leaders seem to have decided not to give the terrorists what they were looking for - the cancellation of the summit.
Peter Hunt : Liverpool Street : 1205 BST
People here really are struggling to resume their working lives and there are lots of people standing around in huddles - there's little appetite for work. Others are trying to make their way by foot as it is impossible for them to make their way by any other means within the City of London. Large numbers of streets and roads are closed. I passed 12 London buses who'd been advised not to move. The emergency services are trying constantly to stop people from hanging around near the cordon - quite extensive forensics work is going on on the underground well away from prying eyes.
Dominic Casciani : Aldgate East : 1200 BST
It's midday in what should be one of the busiest parts of the city, but all the areas surrounding Aldgate East have been cordoned off, leaving city office workers trying to make head or tail of what is going on. At the Minories entrance to the cordon, eight London firefighters have just left the scene, covered in grime and looking pretty exhausted.
But for anyone on the outside of the cordon it is very difficult to know what is really going on as the London security plan swings into action.
Jim Wheble : Aldgate : 1159 BST
There have been a lot of ambulances coming up and down to Aldgate. Looking up from street level, I saw six or seven army officers in fatigues surveying Liverpool Street with binoculars from the rooftops.
Offices have been evacuated around Aldgate, with people coming out of their offices and not knowing what is going on. The situation here is a lot more controlled now.
Mark Easton : Kings Cross : 1155 BST
The situation has been developing over the last couple of hours. When I arrived just after 9am I saw some people, walking with now familiar black faces and arms. Since then the situation has developed rather dramatically.
There are 4 double decker buses being used as treatment centres for the less seriously injured. I must have seen 60 or 70 people brought up, many in tears, some with lacerations to their faces. One man was hobbling, another woman in a wheelchair with a very badly injured leg.
Richard Foster: Liverpool Street: 1135 BST
Hounsditch is sealed off and there are police on horseback there. Liverpool Street station is sealed off. The number of people there was in its thousands when I first arrived, but now it has thinned out. The pubs are full round here; people are gathering for news updates and sending texts to let people now they are alright.
Nick Thatcher : Royal London Hospital : 1130 BST
The Royal London Hospital have been receiving casualties all morning. This is a major hospital in East London. There's an air ambulance landing on the roof behind me. There are buses behind me which have come from the Kings Cross area in central London. On board are walking wounded who have been ferried here.
Jon Brain : Edgware Road : 1115 BST
There's been a scene of chaos and confusion all morning here but it's beginning to settle down. The entire area around the tube station has been sealed off and there are dozens of emergency vehicles here.
We've seen a number of walking wounded emerge from the station, many of them covered with blood and obviously quite distraught. They are being treated at a hotel opposite the tube station.
The concern now is whether there are still people trapped inside the tube station underground. I've seen a team of paramedics go into the station in the last half hour.
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